Signs And Symptoms Of Adrenal Fatigue

by Marcelle Pick, OB/GYN NP

Introduction: a new diagnosis

    • Do you feel exhausted, overwhelmed, and stressed all the time?
    • Do you need five cups of coffee or a constant infusion of soda just to make it through the day?
    • Do you have trouble waking up, falling asleep, or staying asleep, no matter which herbal supplements you try?
    • Do you find yourself feeling constantly irritable or on edge?
    • Do you feel that you need to exercise to stay in shape even though you’re exhausted when you do?
    • Do you feel as though everything you eat turns to fat?
    • Are you always hungry, frequently craving sweets, or tempted by “carbobinges?”
    • Are you plagued by irregular or painful periods or PMS?
    • Are you struggling with perimenopause or menopause: lowered sex drive, vaginal dryness, mood swings, and hot flashes?
    • Do you find yourself feeling forgetful, “foggy” or unable to concentrate?
    • Do you find that you do better when you’re always on the go?
    • Do you find that you actually enjoy adrenaline rushes and feel a little bored without a crisis to handle?
    • Are you struggling with anxiety, depression, or despair?

Sound familiar? If I’ve painted a picture you recognize—in yourself, in your family, among your friends and colleagues—you’ve just gotten a good look at adrenal dysfunction, a distressingly common problem in which overworked adrenal glands produce too much cortisol, the stress hormone.

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Adrenal Health In Women

by Marcelle Pick, OB/GYN NP

We’re all familiar with stress — it’s a constant element in women’s busy lives. But what we aren’t so familiar with is the body’s response to stress and the ways in which the stress we face today goes far beyond the kind of stress we faced as we evolved — and ends up depleting our energy and health.

When faced with a stressful situation, our bodies rely on the adrenal glands sitting atop our kidneys to monitor our “fight or flight” response. For the most part, our stress response evolved from short-term events — crises that came and went. If we had to run from a predator, for example, our healthy adrenal glands responded by releasing adrenaline, which makes us more alert and focused, and cortisol, which converts protein to energy and releases our stored sugar, glycogen, so our bodies have the fuel needed to respond quickly. In concert, the adrenal response rapidly increases our heart and respiratory rates and blood pressure while releasing energy, tensing our muscles, sharpening our senses, and slowing our digestion so we are primed to escape or fight back, whichever is needed. When the threat is gone, the body returns to normal — quickly with respect to adrenaline levels, less quickly with respect to cortisol.

Permission to nurture yourself: Granted!

Stress can help create hormonal imbalance. Nurturing self-care can help restore that balance. If, like many women, you spend a lot of your time taking care of everyone else, it’s more important than ever to make time for yourself. Do something to care for your body, your mind and your soul — like getting a massage, a reiki treatment, even taking a nap or hot bath.

But in today’s society, women are inundated with stress — stress that doesn’t let up. And when chronic stress repeatedly forces the adrenal glands to sustain high levels of cortisol, two things happen: first, the adrenals can’t attend to their broader role in hormonal regulation because the same resources they use to make hormones like estrogen are required to make cortisol, and second, cortisol starts to damage healthy tissues. Eventually, adrenal fatigue sets in, and many women experience symptoms such as weight gain, fatigue, insomnia, fuzzy thinking, depression, cravings and mood swings. Once the adrenals become depleted, it can lead to adrenal exhaustion and much more serious health concerns.

There are many ways to replenish adrenal health naturally. One thing I can promise you is that when you heal your adrenal glands, you’ll see results on every physical and emotional level, and your whole body will thank you for it!

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What I Love About Menopause – Understanding What Menopause Is

by Marcelle Pick, OB/GYN NP

How to make these the most vibrant years of your life!

  • The gifts of menopause and post-menopause for women
  • Stamping out the stigma of menopause
  • The journey to menopause: midlife transitions
  • The Women to Women approach to menopause

It astounds me that women are still being told that (and treated as if) menopause and midlife are a disease — something to be avoided at all costs — when the very opposite is true. Menopause is a gift, a lantern lighting the way to significant transformation in all areas of your life. I want you to know, unequivocally, that you can feel and look better than you ever imagined after menopause, even if your symptoms right now are terrible. It just takes a little help and a lot of self-care. I know this to be true because I’ve experienced it myself and I’ve seen it time and again in my medical practice.

Women to Women sometimes feels like an island surrounded by a sea of negative thinking — especially when it comes to menopause. But from where I sit, the view of midlife is gorgeous: the waters are Caribbean blue, the skies balmy, and the horizon has never looked brighter.

Menopause is a developmental milestone in women’s health — like puberty in reverse — and it’s different for every woman. The word menopause comes from two Greek words: menos or “month” and pausis or “cease”.  At menopause, your ovarian function declines, your menstruation cycle stops, and the monthly spike of reproductive hormones recedes.

This does not mean your body stops making sex hormones altogether — it means you don’t get your period and, if you haven’t menstruated for over 12 months, you almost certainly won’t get pregnant. So go ahead and throw out those tampons and Kotex and buy yourself some nice new underwear. The cessation of monthly cycles can be incredibly liberating.

This doesn’t mean there won’t be some stormy seas. It means that paradise doesn’t come in a pill — it comes from finding out who you really are, what your body really needs, and what you really want to do with this part of your life.

So let’s brave this new sea and swim for shore — I promise you, the water is fine.

The gifts of menopause and post-menopause for women

Once a woman reaches menopause, life gets simpler. Post-menopausal women can maintain regular cycles of energy with much less fatigue. Plus, strange food cravings and binges disappear, as do monthly mood swings and breast tenderness. And there are no more awkward moments walking backwards out of a restaurant with your sweater tied around your hips.

The secret no one tells you is that midlife can be the most radiant, passionate years of your life. Self-knowledge and self-confidence are the true gifts of menopause — they create an inner glow that more than cancels out other physical changes. One patient describes it as finally owning her skin after years of struggling to pay rent.

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You may be asking: what about aging, wrinkles and weight gain? What about becoming metaphorically invisible? Surely there must be something backing up those dried-up menopause clichés. After all, if menopause is so great how come there’s so much bad press?

Well, it’s a fact that everyone gets older every day and this comes with some inevitable physical changes — it’s a price we all pay for getting to stick around. Gravity does exert its pull — but menopause is not the wicked witch. She does not drain women of any vital function nor turn them old, weak, crotchety, or unattractive with a wave of her wand. We do that to ourselves by buying into a prepackaged idea of what being older (and younger) means.

It’s time to retire that tired old stereotype of the post-menopausal woman and take a good look at the real women who are living it.

Stamping out the stigma of menopause

Lauren Bacall once said during midlife, “I am not a has-been, I’m a will-be.”

Just think of the number of highly successful, gorgeous women now in their 50’s and beyond (Kim Basinger, Oprah, Vera Wang, Diane Sawyer, Patti Labelle, Goldie Hawn, Suzanne Somers), and you get an exciting look at the new face of menopause. There’s a reason they’re saying that 50 is the new 30.

Urinary Incontinence — Help For Female Bladder Problems

by Marcelle Pick, OB/GYN NP

Don’t just live with urinary incontinence — learn about the causes of incontinence and what you can do about it! Here are the topics discussed in this article:

The other night I was at a charity event and a friend introduced me to a group of eight women whose ages ranged from 35 to 50. One of them asked me what I was working on and I decided to be frank and say I was putting the finishing touches on an article about urinary incontinence in women.

You should have heard the outcry! Each woman had a different story to tell. One had to leave her aerobics class after her shorts got soaked. Another abandoned a grocery cart full of food in the check-out line to sprint for the public bathroom. Another organized her day around easy access to the toilet.

Every woman in that group (some were mothers, others were not) had some experience of losing bladder control. Most seemed to think it was an inevitable part of aging — complete with the requisite adult diapers or incontinence surgery.

Stress incontinence and overactive bladder (OAB, also known as urge incontinence), or a mixture of both, are extraordinarily common — but nobody wants to talk about them. In the past, traditional medicine viewed incontinence as primarily a men’s issue. But in my experience nearly all women suffer at some point in their lives from some form of urinary incontinence. What’s more, our bladder control issues can suddenly leap from moderate (or nonexistent) to severe with the onset of menopause, and especially take women who have never experienced childbirth by surprise.

It’s high time we bring urinary incontinence out into the light and talk about it. Women are so conditioned to suffer in silence, but stoicism that leads us to keep our health concerns quiet is not good for our health. In fact, women rarely mention urinary incontinence in their annual visits with me. So I ask! Incontinence may not be entirely avoidable as we get older, but it is certainly treatable, and there are very effective alternative methods. Let’s discuss what can be done both to prevent and to find relief from female bladder problems.

What is female urinary incontinence?

A sudden urge to go, leaking urine, and frequent urination are all forms of urinary incontinence, which is generally defined as a lack of bladder control. While there are many causes, the most basic is a gradual weakening of the pelvic nerves, organs and smooth muscles that are meant to work together to control urination.

The bladder itself is a sac that stores urine from your kidneys. When it’s full, pelvic nerves send a signal to the brain that you have to “go.” Your pelvic muscles, especially the sphincter of the urethra, clench, and “hold it” until you get to the bathroom. Once you’re there and safe, your brain tells the sphincter muscles to relax and your bladder empties.

Believe it or not, the muscle anatomy “down there” is still not completely understood by modern medicine. We do know it’s an intricate and amazing arrangement of dozens of muscles which keeps things in and lets them out as necessary. Naturally, the female pelvic floor is much more complex than the male pelvic floor because women have babies.

But a lot can change in the course of a lifetime. Inner pelvic muscles stretch and atrophy with age, pregnancy, gravity and trauma. Muscles can lose their elasticity with lack of use and loss of estrogen. Organs actually move around, often pressing on the bladder itself. In some cases the bladder or urethra may become damaged or chronically inflamed and malfunction. Scarring from surgery, injury or infection may disrupt the natural alignment of the organs inside the pelvic area.

And when you think about it, which of us doesn’t experience several of these factors over time?

House beautiful: the anatomy of the pelvis

You may have noticed the anatomical chart in your healthcare provider’s office of a woman’s internal organs. In that image, all of our parts are stacked neatly and well-supported within cushioning bands of smooth muscle. The vagina and the uterus nestle snugly between the urethra and bladder in front and the rectum and colon just behind.

There are several important ideas I want you to grasp from this picture to help you understand the help we have to offer for urinary incontinence:

  • This elegant anatomy relies on the strength and tone of our pelvic muscles and ligaments, particularly the pelvic floor and perineum, to keep everything in its proper place.
  • There is a lot of complexity in a small area — where our urinary tract, our reproductive tract, and our intestinal tract all converge. Changes in one of these systems can and do affect another.
  • The bladder — and all the pelvic tissues and organs — are exposed to so many adverse developments in this picture, from posture to digestive problems, and some number of those adverse developments are inevitable as we get older.

Types of bladder problems

Before we talk about how to relieve incontinence (sorry for the pun, but we have to keep our sense of humor!), let’s explore the different types of incontinence that women experience.

Stress urinary incontinence (SUI), also called light bladder leakage (LBL), is related to the weakening of the pelvic floor resulting in pressure (or stress) on an otherwise fully functioning bladder. One minute you’re laughing, sneezing or coughing, the next moment your underwear is wet. I know very few women who have not experienced some degree of stress incontinence at some point or another. Exercise (particularly jumping), orgasm, and even hearing running water can trigger it — often with greater regularity after menopause. It’s true that pregnancy and childbirth and pregnancy are frequently to blame for stress incontinence, but we also see a lot of women with stress incontinence at our practice who have never borne children.

Urge incontinence (UI) or overactive bladder (OAB) is a sudden, uncontrollable need to go, even if you just went ten minutes ago. It’s a result of uncontrolled contractions of the bladder muscle (called the detrusor) caused by a disruption in communication between the bladder and the brain. This happens due to inflammation of the bladder lining, infection, injury, natural atrophy that comes with age, or other reasons. Waking up once to several times at night to pee, called nocturia, is a common OAB complaint, as is accidental wetting due to an unstoppable urge to void. Sometimes overactive bladder is the result of overflow incontinence (see below).

Prescription medications for urge incontinence can either relax the detrusor muscle (e.g., Sanctura) or block the nerve impulses that prompt the bladder to contract (e.g., Detrol), which can be helpful for OAB, but they do not relieve symptoms of stress incontinence. They can also cause many side effects, including dry mouth, constipation, headache, blurred vision and dizziness, to name a few.

Many of our patients come to our medical clinic with a combination of both stress and urge incontinence, which is classified as mixed incontinence.

Overflow incontinence occurs when you can’t evacuate all the urine in your bladder because muscle tone is weak or you have a blockage. Symptoms of overflow incontinence include dribbling, urgency, hesitancy, straining, a weak urine stream or low urine production even though your bladder feels full. It’s more common in men, but overflow incontinence occurs in a significant number of women as well.

Once you and your healthcare provider have a better idea of what type of urinary incontinence you’re experiencing, you will have a better chance at getting to the root causes and deciding on the best form of treatment.

What causes incontinence in women?

Sometimes the smooth muscle of the vaginal wall or the perineum overstretches and herniates, allowing the bladder or urethra to balloon through the weakened muscle. This herniation creates a pocket in the vagina known as a cystocele or urethrocele, which makes it difficult to fully empty the bladder or stretches the opening of the urethra, causing stress incontinence. You can usually feel a cystocele or urethrocele as a smallish, smooth bulge in the anterior (front) or side wall of your vagina. Overstraining, childbirth, and injury are the most common causes of cystoceles and urethroceles prior to menopause. After menopause, the natural thinning of the muscles is the more common culprit.

Chronic infection, surgery, medications (including synthetic HRT), radiation, adhesions, and disease are other factors that affect bladder function and the architecture of the muscles and nerves in the pelvis — and they can all contribute to issues with incontinence.

You are more likely to develop urinary incontinence if you have had significant trauma to the pelvis, spine or bladder, surgery, a disability or impaired mobility (which can make it hard to get to the bathroom). We often see a connection between incontinence and a car accident that occurred years beforehand, especially when those accidents were followed by a change in posture or chronic pain. Stroke, Alzheimer’s, multiple sclerosis (MS), and other central nervous system conditions are also associated with urinary incontinence. Some medications can also cause a loss of bladder control.

Systemic yeast, local yeast infections, and food allergies also play a role in bladder infections and interstitial cystitis. And, as in all inflammatory conditions, our emotions play a role in fueling the fire. For more on this, see our articles on inflammation. Smoking, obesity, and chronic constipation (with straining) are additional proven risk factors for developing incontinence over time.

Now let’s spend a moment on the link between hysterectomy and urinary incontinence.

Urinary incontinence after hysterectomy

Hysterectomy increases the odds of incontinence for two main reasons: the design and support of the pelvis is permanently changed, and women often lose the muscle-toning effects of their natural sex hormones post hysterectomy, even if their ovaries have not been removed.

A radical hysterectomy can cause extensive scarring that disrupts your inner musculature and nerves. If at all possible, we recommend having the least invasive hysterectomy available and keeping the ovaries intact. Many surgeons are now capable of performing a laparoscopic hysterectomy, which involves far less damage, or a modified procedure to ablate the uterine lining or embolize the arteries to the uterus without hysterectomy.

Keeping your ovaries is important when it comes to incontinence because of the beneficial effects of estrogen on the muscles of the bladder, bladder lining, and urethra, and on the connective tissues within the pelvis. Even so, in over half the cases, women who keep their ovaries still suffer some loss of ovarian function after hysterectomy, with negative effects on their hormonal balance. For more information, see our article on hysterectomy and hormones.

Studies also show that synthetic hormone replacement therapy increases a woman’s risk for stress incontinence, and we don’t recommend synthetic HRT in any form but prefer to administer bioidentical hormones transdermally or via lozenges. Topical bioidentical estrogen clearly helps promote a natural elasticity and suppleness in the pelvic floor. We’ve seen patients with UI respond extremely well to bioidentical estrogen cream applied directly to the vaginal wall and particularly the area near the urethra.

Bladder problems after menopause

As if the hot flashes and mood swings weren’t enough, many of us going through menopause start experiencing more episodes of urinary incontinence. A decrease in estrogen initiates a thinning and weakening of the pelvic muscles and connective tissue — our house just starts to sag a little.

The relationship between bladder control and hormonal balance becomes increasingly important as we get older and transition through menopause. Some of us have been keeping an eye on the bathroom all along the way, but what about those women who never had an awkward leaky moment until their 40’s or 50’s?

We’re now seeing more ads for pharmaceuticals directed at female incontinence (somebody finally noticed!). But, as usual, they only address the most obvious symptoms and do nothing to treat the underlying loss of muscle tone. Most of the drugs available act on the muscle spasms related to overactive bladder, but do not treat stress incontinence. What’s more, they can cause other bothersome side effects.

As with any drug or hormone, you need to weigh the long-term risks against the potential benefits before taking a pill that could do serious long-term damage to your health. Of course, we recommend you try the most natural steps first, and resort to drugs only if necessary to get symptom relief.

After menopause, women are more prone to bladder infection, chronic urinary tract infection (UTI) or cystitis. As the urethral muscle loses strength and elasticity due to loss of estrogen, pockets of bacteria can flourish. Taking an antibiotic — nowadays there’s a one-day massive dose — is usually adequate, but in some cases inflammation takes hold and damages the lining of the bladder.

This condition, called interstitial cystitis (IC), is a growing concern in women’s health that warrants an entire article of its own. It’s an inflammatory condition that manifests with all the symptoms of a urinary tract infection even when no bacteria are present. It would not surprise me to find in the future that estrogen imbalance is somehow implicated in the escalating rates of interstitial cystitis that I’m seeing.

The emotional connection to the bladder

In Chinese medicine, the bladder is related to issues of anger and control — there’s ancient wisdom at work when we say we’re “pissed off.”

In yoga, the root lock — or mula bunda in Sanskrit — is located at the base of the perineum. It is one of the three major body locks that control our inner life force, or kundalini. (Note that this inner life force is considered to be female!) It is closely related to the earth and the force that connects all living things. Lifting the mula bunda creates stability and energy within the body, channels our life force up through the chakras, and imbues our bodies with a sense of weightlessness. You can access this life force with kundalini yoga postures and Kegel exercises, as discussed below.

Incontinence can sometimes be a physical manifestation of some deep-seated fear or worry that weighs us down. It’s often related to anxiety or anger about losing control. Occasionally, sporadic episodes of incontinence will occur during a particularly stressful — or “out-of-control” — phase of your life. Pay attention to your feelings and see if you notice any patterns.

Urinary incontinence treatment — what you can do right now

Bladder issues are like so many health-related concerns — the sooner you attend to them the easier they are to treat. So here’s what you can do:

See your healthcare provider. If you are noticing any urine leakage or an increased frequency of urination, the first step is to get checked out by your healthcare practitioner. Depending upon the situation, you may find it useful to consult further with a gynecologist, urogynecologist, or urologist.

When we see women for bladder problems, we first try to figure out what kind of urinary incontinence they are dealing with. Most often this is some form of mixed incontinence that can be treated through alternative therapies.

Pelvic floor exercises. In cultures where women squat to do their work, there is a much lower incidence of incontinence. Most women don’t do much in the way of that kind of labor anymore — but we’ve got Kegel exercises! Incontinence can often be arrested or reversed with Kegel exercises alone. Named after an American ob/gyn, these simple exercises are really an adaptation of the “root lock” of kundalini yoga without the trappings. You can do them anywhere, anytime — and you should.

To do a Kegel, imagine that you are trying to stop yourself from urinating. Practice both short and long Kegels. You can even do an anticipatory Kegel before you sneeze or cough and prevent leakage! For more information on Kegel exercises for urinary incontinence, visit the University of Iowa Hospital and Clinics’ website.

A wonderful added benefit of Kegels is that the increased muscle tone can increase sexual pleasure in both sensation and orgasm. Male partners are happier too!

Sometimes women have trouble identifying the muscles that control the bladder and get frustrated attempting Kegels. This can be a natural result of conditioning the brain to ignore bladder stimulation. How many of us are too busy to go to the bathroom when we feel the urge, then “forget” we had to go. Over time, it’s possible that our brain just stops paying attention and we disconnect. It can take some work to get those pathways talking again.

If Kegel exercises don’t seem to be working well for you, you can try insertable cones or balls (available through your doctor or on the internet) to help you train your PC (pubococcygeal) muscle. Biofeedback practitioners use electronic monitors inside the vagina to help women learn how to identify and tone muscles related to the bladder. Both tools can be very effective.

Any kind of physical exercise that engages your core will help strengthen your pelvic muscles, but Pilates and yoga in particular are great inner toners. Both focus on building a firm core or root. They also use deep breathing and mindful movement to reconnect the brain to the body.

Acupuncture is another method that has provided symptomic relief for some women. It helps tone muscle and increase blood flow to the bladder. It can boost the immune system, soothe inflammation, and restore balance to the hormones.

Pelvic physical therapy (PPT) is sometimes effective in difficult cases. Practitioners use several diagnostic tools, including sonograms, physical exams and lower back screenings to evaluate the cause of incontinence. Treatment may include external and internal pelvic floor massage, relaxation training, biofeedback, strengthening, bladder retraining, and home exercises. This is especially useful when patients have adhesions or physical anomalies due to radiation treatment, injury or surgery. Many women who undergo PPT report increased libido and enjoyment of sex in addition to better bladder control.

Nutrition is vital to restoring a healthy balance to your endocrine and immune system, which in turn is important for maintaining muscle tone and preventing infection. Eating a diet of whole foods with plenty of fruits, vegetables, protein and some whole grains will promote adequate nutrition and help level out your hormones. Be sure to take a robust multivitamin/multimineral formula to support your body. And try supplements with cranberry extract — just be sure they don’t have added sugar.

Allergies may exacerbate an overactive bladder. If you think you may have food allergies or sensitivities, we recommend trying an elimination diet (avoiding a suspicious food for two weeks, then re-introducing it for a day or two).

Drink plenty of water and herbal tea. Flushing your urinary tract regularly will help evacuate bacteria. Cranberry juice and extracts can help prevent urinary tract infections by changing the pH of the bladder, but again, be sure you choose one with no added sugars. (Excess simple carbohydrates in the diet only encourage UTI’s).  If you are getting up in the middle of the night to urinate, stop drinking a few hours before bed.

Internal or surgical methods. If you’ve tried everything and you still can’t go out for an evening without worrying, you may want to consider a form of internal intervention. If urinary incontinence is keeping you from fully enjoying your work, love life, hobbies and pursuits, then fitted internal devices or surgical interventions are a reasonable next step.

Fitted pessaries, sometimes referred to as prolapse pessaries, are removable umbrella-like support rings that can help lift your pelvic organs up off your bladder. A pessary can be a great non-invasive choice for a woman with a cystocele or uterine prolapse.

New techniques like bladder laparoscopy and bladder slings can be helpful for treating severe stress incontinence in some women. Currently the most common procedures are known as the Burch colposuspension technique and the fascial sling. In the past, bladder suspension surgeries had a useful life of about four years. In the Burch, the urethra and bladder are secured with sutures to the pelvic wall. The new bladder slings use life-like materials that move with the body and act like real muscle.

Unfortunately, however, a study published recently in the New England Journal of Medicine suggests that neither of these surgical procedure offers terrific results for the women who have them. Known as the Stress Incontinence Surgical Treatment Efficacy Trial (SISTEr), the fascial sling was compared with the Burch colposuspension technique for treating stress urinary incontinence — the type of leaking that can occur when we run, laugh, sneeze, cough, or lift heavy objects. A mere two years following surgery, only 47% of the sling patients and 38% of the Burch suspension patients experienced good resolution of their stress urinary incontinence. Even so, the better results of the sling appeared to be offset by higher rates of UTI’s, problems with voiding, and even urge incontinence.

As with any surgery, we recommend getting as much information as possible and discussing your options with a few practitioners. More progressive doctors are using the latest technology to re-engineer a leaky bladder without excessive trauma and scarring. There are now gynecologists who specialize in urology (urogynecologists), and more women are going into urological surgery (formerly an exclusively male specialty). It’s safe to say that the more experience a surgeon has with a procedure, the more likely it is that you will experience the results you are looking for.

Emotional work. Understanding our hidden fears and anger or reluctance to “let go” can be a powerful remedy in dealing with incontinence. Many women have found relief with the Feldenkrais method — a mind-body technique that can help heal physical conditions through the release of emotional blockages with movement.

Because the brain and the bladder are intimately connected, it only makes sense to approach incontinence on both fronts.

Don’t just live with incontinence

I know there isn’t an easy remedy for urinary incontinence. Gravity, aging and loss of estrogen are pervasive. But like so many problems with our bodies, let’s focus on what we can control — because that’s how we’ll find solutions. I feel for every woman whose life is compromised by urinary incontinence. With a willingness to talk about it and experiment with changes, we so often see great improvement.

The Benefits And Risks Of Fosamax And Other Bisphosphonates

by Marcelle Pick, OB/GYN NP

Early use of bisphosophonates—the class of drugs that includes Fosamax (alendronate), and Actonel (risedronate), was industrial: corrosion prevention, laundry soaps, and fertilizer. They were used primarily in the textile and oil industries.

Scientists only discovered that bisphosphonates inhibit bone resorption (or bone loss) in the late ‘60s. Bone scans proved that the drugs increased bone density as long as they were taken regularly. FDA approval of Fosamax for use in the treatment and prevention of osteoporosis occurred in 1995. Since then these osteoporosis drugs have quickly gained market share, fueled by dire warnings of the impending osteoporosis crisis.

There have been no studies how these drugs effect bone and overall health with long-term use. The longest study spanned three years. And now that we know that inhibiting bone loss also inhibits new bone growth—its very likely that we are creating a generation of women with dense but old and brittle bone. But how will we know?

Since almost 40% of women over 50 are considered at risk for osteoporosis, it seems we are in the midst of yet another grand public experiment the scale of which rivals the early days of Hormone Replacement Therapy (HRT). It’s what the industry calls “post-market surveillance” and you are paying for it.

Merck, the parent company of Fosamax (as well as Vioxx) claim that their drug is safe is taken as directed (upon rising, with a full glass of water at least 30-60 minutes before breakfast). Inflammation of the esophagus and stomach lining can occur if you lie down too soon after taking the pill. They assert that long-term use has no ill affect.

While this may be true for women who use the drug for a limited time (6-24 months), over time the side effects appear to worsen. Women taking Fosamax for more than a couple years report serious bone and joint aches and increasing pain and discomfort (perhaps a side effect of accumulating old bone with no new bone growth?).

What’s more, a 1993 report discovered that a small percentage of bisphosphonate users experienced serious eye problems that could lead to vision loss; one third of the study group complained of blurred vision. More troubling is the small group of people in a recent study who were on corticosteroids and then Fosamax-like drugs: 1 in 12 had their jawbone deteriorate.

I see this borne out in my practice all the time. Women come to me on Fosomax who are experiencing the beginning of systemic failure—which makes sense when you think that this is a class of drug in the same family as cleansing powders! What’s more, most of these women could do more to prevent bone loss by making certain lifestyle changes, without the risk. Afterall, to get FDA approval, you only have to prove your drug is more effective than a sugar pill.

If reading the news about Vioxx and other drug recalls is not enough to convince you that pharmaceutical companies have their bottom line at heart, not the public’s interest, consider this quote from FDA employee and whistle blower Dr. David Graham: “But, when there are unsafe drugs, the FDA is very likely to err on the side of industry. Rarely will they keep a drug from being marketed or pull a drug off the market… There’s no incentive for the companies to do things right. The clinical trials that are done are too small, and as a result it’s very unusual to find a serious safety problem in these clinical trials. Safety flaws are discovered after the drug gets on the market.”

I think it’s time we stop being guinea pigs. Osteoporosis is an easily preventable and highly treatable disease—it just takes a little work.

For more information, read our many informative articles in our Bone Health and Bioidenticals and HRT sections.

 

The Truth About Cholesterol and Fat

by Marcelle Pick, OB/GYN NP

Like so many of my patients, for years I tried one low-fat, low-cholesterol diet after another. But after failing to lose weight — and feeling pretty bad despite my “healthy diet” — I did a panel of blood tests on myself. The results were shocking.

That fateful day was 25 years ago. It began my personal search for the truth about cholesterol and fat. What I learned at first surprised me, but now makes perfect sense. And I’ve proven it all in practice, both personally and with thousands of patients.

What surprises me today is that there is still so much confusion about cholesterol and fat. Over 70% of my new patients are still afraid of eating fat — any fat. They think eating fat will make them fat and raise their cholesterol. They think a low-fat diet will help them lose weight and help prevent heart disease.

Unfortunately, none of that is true. In fact the opposite may be true, especially for women. So let me share with you what I tell my new patients about cholesterol and fat. You may be in for a surprise.

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Don’t feel guilty about cholesterol and fat

In my low-fat phase, I always used to feel guilty about enjoying fatty foods. But I learned that the human body is hard-wired by evolution to crave cholesterol and fat — so don’t feel guilty!

You crave cholesterol and fat because they’re essential to your health. When you eat real cholesterol and fat, you regulate insulin levels and trigger enzymes that convert food into energy. Cholesterol from food modulates your body’s internal cholesterol production and protects liver function.

What are essential fatty acids (EFA’s)?

Before we get into the role of fat in the body, let’s touch upon the most important type of fat you need to feed yourself. Without a doubt, essential fatty acids are just that — essential. They cannot be synthesized in the body and must come from dietary sources. However, while only two of the fatty acids are technically “essential”, all omega-3 fatty acids are in critically short supply in the average American diet for the following reasons.

Some fatty acids, in particular the omega-3s, lower triglycerides and soothe inflammation, helping the liver convert pro-inflammatory blood acids like homocysteine into anti-inflammatory agents. The omega-6s generally play a pro-inflammatory role, but there is evidence that at least one omega-6 fatty acid (gamma linolenic acid, or GLA), found in black current and evening primrose oils, also prevents negative inflammatory effects. Without getting into the biochemistry in too much detail, what is important to note here is that your body works as a seamless, well-greased system when the ratio of one type of fatty acid to another is in balance.

The Menstrual Cycle

by Marcelle Pick, OB/GYN NP

A woman’s menstrual cycle is highly individual, and can range anywhere from 24–37 days. What’s “normal” is what’s normal for you. The length of your cycle may be affected by many things, including illness, stress, travel, fertility medication, and close association with other women.

At different times in your life, your menstrual cycle may become irregular due to a variety of factors, including pregnancy, stress, diet, hormonal imbalance, exercise, and illness.  For more information, refer to our articles on irregular periods.

Let’s consider a typical 28–day cycle, and call the first day of bleeding day 1.

Menstrual Cycle Diagram

Menstrual Cycle Diagram – © 2014 Women to Women*

Each month our ovaries begin to ripen a number of follicles, which is why days 1–14 are called the follicular phase. Each of the many follicles in the two ovaries is a pocket of tissue filled mostly with estrogens. The number of active follicles changes with each cycle, but typically only one follicle per month in a single ovary becomes dominant over the others and produces a viable egg. As the follicles ripen, estrogen levels rise.

Just before mid-cycle, the hypothalamus and pituitary gland release LH (luteinizing hormone) and FSH (follicle stimulating hormone) spikes to trigger the dominant follicle to ovulate. Estrogen levels continue to rise.

Days 14–28 are termed the luteal phase, when estrogen levels begin to fall and progesterone levels rise. Around day 14 (but it can vary) ovulation occurs.  The dominant egg is released from the follicle and is drawn into the fallopian tube on its way to the uterus. This triggers a host of hormonal secretions — including estrogen — that thicken the uterine lining to support a pregnancy. Many women know they are ovulating by vaginal mucus discharge, nipple tenderness, or the tell-tale twinge in their abdomen called mittelschmerz.

Women are fertile for about 24–48 hours around the time of ovulation. Progesterone levels remain high unless the egg goes unfertilized, in which case the egg is re-absorbed and progesterone levels fall. In this event, progesterone levels continue to fall until day 28, when progesterone reaches its lowest level, menstruation occurs, and the cycle repeats. This turning point almost always occurs 14 days after ovulation.

The Link Between IBS, Acid Reflux And Antacids

by Marcelle Pick, OB/GYN NP

Most of us think of irritable bowel syndrome in relation to our intestines. It’s useful to know that many women with a diagnosis of IBS also complain of symptoms in their upper GI tract: heartburn/acid reflux, nausea, and stomach pain. These upper GI symptoms are often related to the rate at which the stomach empties. If the gastric environment is out of balance, the stomach tries to squeeze out its partially digested contents from both ends as quickly as possible. This leads to a burning sensation that many of us self-medicate with antacids.

Unfortunately, using antacids will not get at the root cause of your upper GI symptoms, and might even make the problem worse. In my experience, acid reflux and chronic heartburn can actually be the result of too little acid in the stomach — not too much. Overuse of antacids will initially lend some relief only to end up aggravating the underlying condition. In addition, antacid use can lower the acidity of the stomach to such a degree that it loses its ability to protect us from bacterial infection. It is now widely recognized that bacterial infection can cause ulcers.

Of course, if you are currently taking a prescription medication for heartburn, like Nexium or Prilosec, do not stop taking it except with the advice of your primary care provider. If you’d like to seek an alternative (of which there are many), look for an alternative practitioner in your area.

At Women to Women, we have seen most cases of chronic heartburn resolve themselves when women pay more attention to their diet and provide their bodies with nutritional support. An elimination diet can help identify the foods that might be triggering your symptoms. Eliminate a suspicious food for a week and see if your symptoms subside without antacids. We also put all of our patients with acid reflux on a medical-grade multivitamin, which provides the nutritional supplementation necessary for balanced intestinal flora.

Sugar Substitutes and The Potential Danger Of Splenda

by Marcelle Pick, OB/GYN NP

Few of us are really aware of how many Splenda® products there are in the supermarkets. We’ve been told that this artificial sweetener is different from all the past failures — Sweet’N Low®, NutraSweet®, etc. — and according to the claims, that Splenda is the perfect sugar substitute: as sweet as sugar, SS Spoon With Sugar Redbut no calories; as sweet as sugar, but no surge in insulin; as sweet as sugar, but no side effects or long-term health damage.

“Low–sugar” or “sugar–free” is a welcome trend, given the health hazards of all the sugar in the average diet. But of the hundreds of new diet foods that constantly appear, most will use Splenda as a sugar substitute. This is important because for tens of millions of women, their diet soda or artificially-sweetened food is a keystone of what they think are healthy nutrition and food choices — both for themselves and for their families.

On the other side of the argument are responsible experts who say that Splenda is unsafe — the latest in a succession of artificial sweeteners that claim at first to be healthy, only later to be proven to be full of side effects. These authorities say that Splenda has more in common with DDT than with food.

What do we believe? We think that our regulatory system doesn’t do a good enough job ensuring our long-term safety. We’re concerned about the bigger picture, too — the dependence on sweets in the American diet to make us feel good — whether those sweets are satisfied by sugar or artificial sweeteners like Splenda. And we are especially sensitive to the women who can benefit from using artificial sweeteners as a bridge to a better life with healthier nutrition.

What should you think about artificial sweeteners? We want you to be fully informed about the dangers of Splenda (which isn’t what food marketers want!) so you can make the best choices for yourself and for your family. So let’s make sure you are.

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Splenda — the public health experiment

“Low–sugar” is the successor to the “low–carb” craze, even though they are essentially the same thing. According to the New York Times, by the end of this summer 11% of the food items on supermarket shelves will be labeled “reduced sugar” — most of those targeted at kids and their health-conscious moms. SS Sugar SubstitutesSales in granulated sugar have dropped four percent in the past six months. What’s behind this trend? Splenda.

Products featuring Splenda are perceived as “natural” because even the FDA’s press release about sucralose parrots the claim that “it is made from sugar” — an assertion disputed by the Sugar Association, which is suing Splenda’s manufacturer, McNeil Nutritionals.

The FDA has no definition for “natural,” so please bear with us for a biochemistry moment. Splenda is the trade name for sucralose, a synthetic compound stumbled upon in 1976 by scientists in Britain seeking a new pesticide formulation. It is true that the Splenda molecule is comprised of sucrose (sugar) — except that three of the hydroxyl groups in the molecule have been replaced by three chlorine atoms.

Reducing Inflammation — The Natural Approach

by Marcelle Pick, OB/GYN NP

Woman Relaxing PeacefulOver many years we have found that preventing or reversing inflammation is all about listening to your body. From that listening you can begin to learn first-hand what increases or reduces your body’s inflammatory response. You can cool your body’s inflammatory response and keep it healthier over time by taking one step at a time, at a pace that feels right for you. This is the approach we have found to be most effective and sustainable over the long term.

You have many options for reducing inflammation. Many of the suggestions we recommend can be implemented on your own. But if you have chronic inflammation, or moderate to severe symptoms of inflammation, we encourage you to work with an integrative healthcare or functional medicine provider to devise a plan that suits your unique needs.

The anti-inflammatory diet

You may want to investigate the comprehensive anti-inflammation diet outlined in my book, The Core Balance Diet. But here are three ways to deliberately counter inflammation in your diet today:

Basket of Fish and Fresh VegetablesEat lots of fruits, vegetables, and wild seafood. Add generous portions of deeply-pigmented vegetables to every meal and snack for their fiber and natural anti-inflammatory compounds. Many herbs and foods such as turmeric, oregano, garlic, green tea, blueberries, and ginger contain bioflavonoids and polyphenols that limit free-radical production in the body.

As for fish, while its health benefits were once beyond compare, many species today contain astronomically high levels of mercury, PCB’s, and other toxins. With that unfortunate reality, we suggest you significantly limit or avoid Atlantic varieties, and eat only wild Pacific or Alaskan salmon (unless organically farm-raised). Because toxins magnify as you go up the food chain, smaller species such as sardines, anchovies, and shellfish are still good choices.  For more information, check out EWG’s Consumer Guide to Seafood.

Add essential fatty acids (EFA’s) to your diet, such as the one formulated by Women to Women. Because omega–3 fatty acids are in shortest supply in our modern diet, we recommend you take an omega–3 supplement daily to rebalance your diet. This is one of the simplest, safest, yet most effective steps you can take to quell chronic inflammation in your body. In our practice we have found fish oil EFA supplements to be most helpful, but if you are a vegetarian, algal sources can be used with good result. Just be sure your EFA supplement has been tested and proven free of mercury and other heavy metals — otherwise it might do you more harm than good.  Click here to find out more about Women to Women’s EPA/DHA Fish Oil Support Formula.

Inflammation Diet Nuts SeedsWe also encourage you to include a small handful of nuts and seeds in your diet daily, especially walnuts and freshly ground flaxseed, which are good sources of omega–3s. Some practitioners also recommend adding an omega–6 supplement called gamma linolenic acid (GLA) if you have rheumatoid arthritis. For cooking purposes our oil of choice is grapeseed oil, and for dressings it’s olive oil, which is high in oleic acid, an omega–9 with anti-inflammatory polyphenols. You can even have the ratio of EFA’s in your blood measured with an EFA profile that evaluates omega–3 levels versus omega–6s versus omega–9s. Remember, when it comes to essential fats, it’s all about balance — read our articles about about fat and cholesterol, the benefits of omega-3’s, and the differences between omega-3’s, 6’s and 9’s for detailed info.

Eliminate certain foods and additives from your diet. I know how hard it can be to say no to the many foods that turn the body’s inflammatory dial up high. Number-one on the list of offenders would be trans fats — hydrogenated oils. Next would be the sugars, refined carbohydrates, and gluten-containing foods that women often crave when their systems are off-balance. These and many other additives and preservatives are well hidden in processed convenience foods, making them very difficult to avoid.

You will also need to steer clear of known allergens, and be aware of increasing food sensitivities as well. Gluten, eggs, dairy, soy and nuts are some of the most common dietary irritants. To help you identify sensitivities that could be causing you problems, follow an elimination diet, avoiding a substance for two weeks, then reintroducing it for a day or two. Yes, it can be tough at first to make changes like this, but the payoff is huge — it can make a tremendous difference in how you feel in a surprisingly short period of time. Tipping the balance — away from pro-inflammatory, toward anti-inflammatory — can take place almost overnight for some women.

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